CYP7B1 and metabolic dysfunction-associated steatohepatitis: A potential transition in the alternative BA synthesis pathway mediated by increased CYP7B1 mRNA and protein expression was observed in subjects with NASH(Lake et al., 2013), which is presumed to be a self-protective mechanism in the liver, but its products may play a role in NASH-HCC(Jia et al., 2021).