MGMT and glioblastoma: Moreover, we analyzed the relationship between CCNScore and LGG molecular phenotypes and found that the high-CCNScore group significant concentrated in IDHwt, Classic-like, mesenchymal-like, IDH1mut/TERTmut, MGMT promoter unmethylated, gain chr7and loss chr 10, gain chr 19/20, TERT telomere maintenance, TERT promoter mutant subgroup, as well as NF1mut, PTENmut and EGFRmut subgroup, showing a GBM-like molecular signature.