SLC7A11 and breast cancer: Cobler et al. finds that inhibition of SLC7A11 after Erastin treatment increases radiosensitivity in SLC7A11+ breast cancer cells in vitro and in vivo, while it has no effect on SLC7A11- cancer cells, this process accompanied by a decrease in intracellular GSH synthesis that promotes cell death (Cobler et al., 2018).