The top five DIAPH2-correlated genes in PAAD of TCGA cohort were heterogeneous nuclear ribonucleoprotein F (HNRNRF) (R = 0.76), acyl-CoA binding domain containing 3 (ACBD3) (R = 0.76), minichromosome maintenance complex binding protein (MCMBP) (R = 0.75), KRAS proto-oncogene, GTPase (KRAS) (R = 0.75), and non-homologous end joining factor 1 (NHEJ1) (R = 0.75) (Figure 5C). The gene discussed is ACBD3; the disease is pancreatic adenocarcinoma.