CMTM6 and central nervous system cancer: Elevated expression of CMTM6 in glioma and head and neck squamous cell carcinoma was shown to be associated with a poor prognosis; in addition, CMTM6 is also a potential therapeutic target for triple-negative breast cancer (Hou et al., 2020; Jin et al., 2020; Tian et al., 2021; Zanotelli et al., 2021).