PLOD1 and polycystic ovary syndrome: A study showed that the serum T, estradiol (E2), LH, LH/FSH were reduced and the serum FSH was increased after given 2 ml QUR solution (100 mg/kg) by gavage daily for 28 days in DHEA-induced PCOS rats, whose effects were similar to that of DHEA-induced PCOS rats after metformin gavage in another study (Zheng et al., 2022a).