A study from China also focused on the changes in oxidative stress-related markers in DHEA-induced PCOS rats and the effects of QUR on the expression levels of these markers, which found that serum SOD concentration decreased and malondialdehyde (MDA) concentration increased in DHEA-induced PCOS rats, while serum SOD concentration elevated, nitric oxide (NO) and MDA decreased with QUR administration in PCOS rats (Yang et al., 2021b). This evidence concerns the gene SOD1 and polycystic ovary syndrome.