GLP1R and diabetes mellitus: On the other hand, different diabetes drugs, such as metformin, thiazolidinediones (TZD), glucagon-like peptide-1 receptor (GLP-1R) agonists, dipeptidyl peptidase-4 (DPP-4) inhibitors, and sodium-glucose cotransporter (SGLT2) inhibitors, could be used as treatment strategies for PCOS (Javed et al., 2019; Devin et al., 2020).