TBXAS1 and colorectal cancer: It has been shown that the knockdown of TBXA2R (the gene encoding TXA2 receptor, TP) or TBXAS1(the gene encoding the downstream synthase TXS, which catalyzes the conversion of PGH2 to TXA2) in human colorectal cancer cells resulted in fewer colonies being formed in soft agar than in control cells (Li et al., 2015).