More specifically, compared to adjacent normal tissues, ATP7A, LIAS, LIPT1, LIPT2, DLD, DLAT, PDHA1, PDHB, MTF1, GLS, CDKN2A and DLST was increased, whereas the expression of NLRP3, SLC31A1, and DBT was decreased in HCC. Here, PDHA1 is linked to hepatocellular carcinoma.