311 AD-related proteins were identified as prospective GS-Rd targets from the relevant database and the top 10 core targets were identified using topological analysis and linked to 136 signaling pathways, many of which were connected to the development of cancer, for example, the JAK-STAT signaling pathway, the MAPK signal pathway and other pathways associated with cancer. Here, SOAT1 is linked to Alzheimer disease.