SIRT1 and Sepsis: In addition, Ginsenoside Rg3 increased taurine-upregulated gene 1 (TUG1) expression and decreased expression of microRNA (miR)-200a-3p to stimulate the silencing information regulator 1 (SIRT1)/AMPK pathway, thus enhancing autophagy to improve sepsis-induced liver injury and mitochondrial dysfunction (Wu et al., 2021).