CCL5 and breast cancer: CCL2 and CCL5 have also retained attention in breast cancer, as they are expressed by cancer cells and promote the recruitment of TAMs and metastasis by inducing Th2 polarization of CD4+ T cells (Chavey et al., 2007; Soria and Ben-Baruch 2008; Zhang et al., 2015; Brummer et al., 2018).