BMPR2 and pulmonary arterial hypertension: Further evidence for increased TP expression in the RV in PAH and, potentially in other cardiac dysfunctions, was found in RV specimens from both the Sugen5416/Hypoxia (SuHx)-induced PAH model (Figures 6F,I), and notably from rat strains harboring a mutation in the BMPR2 gene, the primary genetic cause of heritable PAH in humans (Figures 6G,J).