The findings of univariate Cox regression and the Kaplan-Meier analysis indicated that nine CRG (MTF1, CDKN2A, ATP7A, DLD, LIPT1, SLC31A1, PDHB, DBT, and DLAT) had prognostic significance in LC patients (MTF1, CDKN2A, ATP7A, DLD, LIPT1, SLC31A1, PDHB, DBT, and DLAT) (Figure 2(a)). Here, ATP7A is linked to laryngotracheoesophageal cleft.