The findings of univariate Cox regression and the Kaplan-Meier analysis indicated that nine CRG (MTF1, CDKN2A, ATP7A, DLD, LIPT1, SLC31A1, PDHB, DBT, and DLAT) had prognostic significance in LC patients (MTF1, CDKN2A, ATP7A, DLD, LIPT1, SLC31A1, PDHB, DBT, and DLAT) (Figure 2(a)). The gene discussed is DLD; the disease is laryngotracheoesophageal cleft.