The patients with an IC score 2–5 were more predominantly female, had severe obesity, higher prevalence of KDIGO high risk and very high risk categories of CKD, higher rates of both insulin and oral hypoglycemic agents, older age, longer diabetes duration, higher HbA1c, fasting glucose, UACR, and creatinine levels, and lower prevalence of KDIGO low risk category of CKD, eGFR, and hemoglobin levels than those with an IC score of 0 or 1. The gene discussed is INS; the disease is Obesity.