This was confirmed by our study showing that a combination of DT2216 or A1155463 with MCL-1 inhibitor (S63845) synergistically kills not only tumor cells (Fig. 2b), but also normal cells from different tissue origins such as human bronchial epithelial cells (NHBE), colon fibroblasts (CCD-18Co) and lung fibroblasts (WI38) (Fig. 2c; supplementary Fig. 1a). The gene discussed is MCL1; the disease is neoplasm.