SCGN and autism: Given the little available knowledge of the regulatory network for ASD, a better understanding of the interconnection of ASD-associated genes may uncover key features of the heterogeneity of autism in order to develop more effective therapeutic strategies.43 By surveying 1495 genes that were differentially expressed in the hypothalamus of Scgn+/+ and Scgn−/− mice, we found that 90 genes were associated with ASD and 150 were related to immune responses (Fig. 8a, b).