ITPR1 and nervous system disorder: The resulting network suggested that SCGN regulated the oxytocin and the immune response pathways via SNAP-25, whose abnormal expressions and/or mutations have been associated with ASD and other neurological disorders.16 We found that 24 genes, including Camk2b, Adcy5, Cacna2d3, Camk2a, Itpr1, Plcb1, Prkcb, Mef2c, and Ptgs2, were ASD-risk genes that were involved in the oxytocin pathway.