CD8A and neoplasm: Furthermore, we leveraged the TCGA-LUAD and TCGA-LUSC datasets to grasp further information about CD8 T cells subsets infiltration in NSCLC samples high-/low-miR-455-5p expressing: (i) TCGA samples were stratified in ‘High,’ ‘Int’ and ‘Low’ miR-455-5p expressing samples (see Methods); (ii) PD-L1 expression likewise expression signatures related to CD8-exhausted T cells [42] and of IFN response were analyzed in High/Int/Low miR-455-5p tumor subsets (Fig. 7G; see Methods).