PPARGC1A and hepatocellular carcinoma: In the previous studies, no association was found between PPARGC1A rs2970847 SNV and susceptibility of esophageal, colorectal, and hepatocellular carcinomas [31–33], however, the present study showed that it was a protective factor for GC in the group of BMI ≥ 24 kg/m2 in an Additive model.