Out of the differentially expressed miRNAs, hsa-let-7f.-5p, -7 g-5p, -7i-5p, hsa-miR-130b-3p and hsa-miR-28-5p (Supplementary Table S1), and its respective target genes, IL13, IRF1 and STAT5B, were related to several polymorphisms involved in AD in the genetic association analysis (Supplementary Fig. S1). Here, IRF1 is linked to Alzheimer disease.