Notably, AMPKα1 deletion reduced the expression of markers of anti-inflammatory M2 macrophages Ym1, Mannose receptor C-type 1 (MRC1), CD36, CD301 and Glutamine synthetase (GS) (Supplementary Fig. 2b and c), as well as CD169, a marker for M2-like tumour-associated macrophages [25]. This evidence concerns the gene SIGLEC1 and neoplasm.