Since hAECs have been shown to be non-immunogenic and fail to elicit proliferative responses in human peripheral blood mononuclear cells (PBMCs) in vitro [24], we also profiled the hAECs-CRC for expression levels of co-stimulatory markers such as CD80, CD86 and CD105 (Fig. 4C). Here, CD86 is linked to colorectal carcinoma.