IFNB1 and COVID-19: Auto-Abs neutralizing 100-fold lower concentrations of IFN-α2 and/or IFN-ω (100 pg/mL; in 1:10 dilutions of plasma) were further detected in 13.6% of critically ill patients with COVID-19 and 18% of the deceased, while auto-Abs to IFN-β were found in another 1% of critical patients [8].