HAVCR1 and stage 5 chronic kidney disease: Epidemiologic studies of sodium arsenite-contaminated drinking water showed a link for increased risk of developing chronic kidney disease (CKD) and end-stage renal disease (ESRD) and decreased estimated glomerular filtration rates (eGFR) and increased kidney injury marker 1 (KIM1) were observed (Farkhondeh et al. 2021).