CD8A and neoplasm: The extra-TLS immune cells (eICs) studied here included CD20 + pan B cells (eB cell-pan), IgD + naïve B cells (eB cell-naïve), CD8 + cytotoxic T lymphocytes (eCTLs), FOXP3 + regulatory T (eTreg) cells, PD-1 + exhausted T (eTpd-1) cells, EOMES + exhausted T (eTeom) cells, NCR1 + natural killer (eNK) cells, and CD163 + tumor-associated macrophages (eTAMs).