CD274 and neoplasm: Comprehensively, we studied both main immune compartments, the TLS zone, which is just the TLSs, and the extra-TLS zone, with a focus on TLS distribution and maturation, features of intra-TLS immune cells (tICs) and extra-TLS immune cells (eICs), immune ratios, and tumor PD-L1 expression, seeking to reveal the relationship between serum lipoprotein cholesterol and the TIME of GC.