Compared to ALT and AST alone, though, AAR is more strongly predictive for NAFLD onset, which has led to its increased prevalence as a predictive indicator [46]; this was further supported by a study of 12,127 initially non-obese, NAFLD-free individuals, where AAR was found to be an independent risk factor for NAFLD onset in obese individuals [47]. The gene discussed is GPT; the disease is metabolic dysfunction-associated steatotic liver disease.