In agreement with these data, Wu et al. [33], found that the gene expression signature associated with EMT in BCSCs were ITGA6, EPCAM, CCND1, CD44, EGFR, CDH1, and MKI67. Luo et al. [6], reported also that the CD44+/CD24−/EpCAM+ BCSCs play an important role in tumor metastasis, as it showed increased expression of genes responsible for EMT. This evidence concerns the gene CCND1 and neoplasm.