PPARA and familial dilated cardiomyopathy: Among the chemical classes/pathways detected in the DCM group based on diet type but not in the DCM versus healthy control group were those related to polyunsaturated fatty acids (e.g., alpha linolenic and linoleic acid, omega-3 and omega-6 fatty acids), regulation of lipid metabolism by peroxisome proliferator-activated receptor-alpha, multiple G protein-coupled receptors, and mitochondrial biogenesis.