Figure 4 shows the concentration-effect curves ofthe most potent MCT1 inhibitor, compound 24 (A–B),as well as the 2-pyridyl-derivatives 29 (C–D), 30 (E–F), and 31 (G–H) using A-54914,15 (A, C, E, G) and MCF-716 (B, D, F, H)cancer cells. This evidence concerns the gene SLC16A1 and cancer.