We discovered evidence for five shared susceptibility loci (1q41 (ZC3H11B); 2p16.1 (EFEMP1); 6p22.2 (MHC region); 11p13 (WT1); 7q33 (CALD1)) amongst the individual hernia cohorts, of which four demonstrated concordance in allelic effect directions, as depicted in Table 1 and Fig 3. The gene discussed is CALD1; the disease is Hernia.