These loci were also prioritised on combined hernia cohort GWAS analyses with the umbrella hernia cohort analysis resulting in discovery of 14 further shared susceptibility loci including 1q41 (TGFB2), 2p24.1 (GDF7), 3q22.2 (AMOTL2), 5p15.32 (ADAMTS16), 7q11.23 (ELN), 8p21.2 (EBF2) and 12q21.33 (DUSP6). Here, ADAMTS16 is linked to Hernia.