ZC3H11B and glaucoma: Like ZC3H11B, TGFB2 has previously been implicated in ophthalmic pathology including glaucoma endophenotypes, with roles in intraocular pressure [44], central corneal thickness [45], as well as FEV1/FVC ratio [46] and severe chronic obstructive pulmonary diseaseO [47], of which the latter has also been suggested as an independent risk factor for hernia pathology and severity [48, 49].