DDX5 and neoplasm: DDX5 (Cauchy combination test p-value = 0.021), a gene well reported to be associated to breast cancer and regulates DNA replication and cell proliferation [56], had multiple weaker associations with the grade of tumor (p-value = 0.017), overall survival (p-value = 0.004) and HER2 status (p-value = 0.022).