KCNJ5 and adenoma: Only 34% of the APMs studied were identified with mutations in other ion channels/pumps genes such as ATPase, Na+/K+ transporting, α1-polypeptide (ATP1A1) and calcium channel, voltage-dependent, L-type, α1D-subunit (CACNA1D), in contrast to the overall prevalence of 43% of KCNJ5 mutations found in Aldosterone Producing Adenomas (APAs, [46]).