CLK3 and colorectal carcinoma: Considering that autophagy and ubiquitination are two common mechanisms in protein degradation,12 we estimated the protein expression of CLK3 after adding the autophagic inhibitor 3‐MA (2.5 mM) or the ubiquitin proteasome inhibitor MG132 (5 μM) to MFAP2 silenced CRC cells.