Besides, the expression of CLK3 was checked in surgical CRC samples from the GEO dataset of GSE131418 (includes 545 non‐metastatic and 73 metastatic CRC samples), showing that the relative mRNA expression of CLK3 in CRC at M1 stage was higher than that in CRC at M0 stage (Figure S7). Here, CLK3 is linked to colorectal carcinoma.