High intratumoral KLRF1 was associated with improved recurrence‐free survival (hazard ratio [HR] 0.53, p = 0.01), cancer‐specific survival (HR 0.47, p = 0.02), and overall survival (HR 0.54, p = 0.02) on multivariable analyses that adjusted for clinical and pathologic variables. Here, KLRF1 is linked to cancer.