Severe disease was strongly associated with fever, cough, pneumonia, lymphopenia, increased levels of C-reactive protein (CRP), aspartate aminotransferase (AST) and alanine aminotransferase (ALT) activity, older age and male gender (Borges Do Nascimento et al., 2020; Zhang et al., 2020b). The gene discussed is CRP; the disease is lymphopenia.