CRP and lymphopenia: Furthermore, it was demonstrated that lymphopenia, thrombocytopenia, increased WBC and platelet counts and elevated levels of D-dimer, CRP, procalcitonin (PCT), creatinine, and creatine kinase (CK), AST, ALT, and LDH activity were associated with higher risk of poor outcomes and deterioration of disease, including an intensive care admission, oxygen saturation <90%, invasive mechanical ventilation utilization and mortality (Malik et al., 2021; Shi et al., 2021; Xiang et al., 2021b).