TLR4 and cancer: In total, 18 ICD-related genes (AIM2, ANXA1, BAX, CALR, CCL2, CLEC9A, CXCR2, CXCR3, DDX58, IL1B, IL1R1, LRP1, P2RY2, PIK3CA, TLR3, TLR4, YKT6, and ZBP1) were differently expressed in cancer samples in comparison to normal samples (Supplementary Table S2).