In total, 18 ICD-related genes (AIM2, ANXA1, BAX, CALR, CCL2, CLEC9A, CXCR2, CXCR3, DDX58, IL1B, IL1R1, LRP1, P2RY2, PIK3CA, TLR3, TLR4, YKT6, and ZBP1) were differently expressed in cancer samples in comparison to normal samples (Supplementary Table S2). Here, PIK3CA is linked to cancer.