SYNGAP1 and neurodevelopmental disorder: Reportedly, the estimated incidence of SYNGAP1 mutations accounts for ∼0.75% of patients with neurodevelopmental disorders (NDDs) (Berryer et al., 2013; Deciphering Developmental Disorders Study, 2015; Mignot et al., 2016; Weldon et al., 2018; Zhang et al., 2021).