Serine is considered to not only facilitate cancer progress but also maintain neurites’ formation—for example, NGF induces the phosphorylation of RhoA on serine 188 and reduces RhoA–Rho-related kinase for neurite growth (155); another in vitro experiment declaims that NGF-associated phosphorylated STAT3 at serine (727) is involved in neurite growth (156). This evidence concerns the gene RHOA and cancer.