While we have yet to assess the Treg responses following AdPyCS vaccination in the absence or presence of our peptide-based immunomodulators, we recently reported that LD01 treatment of mice infected with a lethal malaria strain resulted in survival that was associated with lower numbers of FOXP3+Tbet+CD4+ Tregs (Phares et al., 2020). The gene discussed is CD4; the disease is malaria.