In addition, the upregulated genes are significantly enriched in “immune response-activating cell surface receptor signaling pathway,” “immunological synapse,” and “immune receptor activity” of gene ontology (GO) bioprocess analysis; in “Primary immunodeficiency,” “cytokine-cytokine receptor interactions,” and “viral protein-cytokine receptor interaction” of kyoto encyclopedia of genes and genomes (KEGG) pathways analysis (Supplementary Figure 1). Here, CD177 is linked to inborn error of immunity.