M6A promotes the replication of DNA viruses, including HSV-1, SV40, AdV, and HPV-16 (30–32, 34), and it has also been shown to positively regulate infection by many RNA viruses, such as EV71, HRSV, HMPV, VSV, and IAV (64, 65, 72–75). This evidence concerns the gene METTL3 and infection.