,5,7 Recent studies have demonstrated that FTO and ALKBH5 can have an oncogenic or tumor-suppressive role in various cancers.4, 5, 6, 7 Additionally, Jin et al. (2022) used The Cancer Genome Atlas (TCGA) database and analyzed the m6A regulatory factors in head and neck squamous cell carcinoma (HNSCC). The gene discussed is ALKBH5; the disease is head and neck squamous cell carcinoma.