To establish the best risk assessment model, we performed Kaplan‒Meier (KM) analysis, and based on the p value of every model, we finally screened out a risk assessment model composed of four genes (MGAM, PTPRB, PAGE2B, RTL1), named RCC-CUPT4 (Fig. 11C, D). Here, RTL1 is linked to renal cell carcinoma.