KEGG pathway analysis indicated cardiac muscle contraction and drug metabolism other enzymes were enriched in high-risk group, while cell adhesion molecules cams, chemokine signaling pathway, cytokine–cytokine receptor interaction, JAK–STAT signaling pathway and pathways in cancer were enriched in low-risk group (FDR < 0.05) (Additional file 1: Fig. S1A–D). Here, SOAT1 is linked to cancer.