METTL3 and colon adenocarcinoma: Based on TCGA pan-cancer correlation analysis, it was demonstrated that ZNRD1-AS1 expression was significantly and positively correlated with METTL3 in all tumor types, with the exception of colon adenocarcinoma (Figure S1B), and with METTL14 in all cancer types (R > 0.3, Figure S1C), including LUAD and LUSC (Fig. 2A-B).