To validate the results of genome-wide DNAm microarray analysis and to determine potential biomarkers for PAE, we examined DNAm profiles of DPPA4, FOXP2, and TACR3 in placenta, WBCs, and BECs from each newborn by targeted DNAm analysis using EpiTYPER (Agena Bioscience, Inc.). This evidence concerns the gene TACR3 and pulmonary artery enlargement.