We found a significant increase in the frequency of \documentclass[12pt]{minimal}\usepackage{amsmath}\usepackage{wasysym}\usepackage{amsfonts}\usepackage{amssymb}\usepackage{amsbsy}\usepackage{mathrsfs}\usepackage{upgreek}\setlength{\oddsidemargin}{-69pt}\begin{document}$${CD39}^{+}{CD73}^{+}$$\end{document}CD39+CD73+ cells in the B-ALL group compared to the control group in the subpopulation of CD8 + T-cells (p = 0.0343, Fig. 6c), and Breg cells (p = 0.0234, Fig. 6d). The gene discussed is ENTPD1; the disease is acute lymphoblastic leukemia.