CD96 and cancer: A hypermetabolic state is indispensable for sustaining CSCs characteristics.[28, 29, 30] Fatty acid β‐oxidation (FAO), a crucial metabolic pathway for maintaining the stemness of cancer cells,[31, 32, 33] plays an important role in the chemoresistance of CSCs.[27, 30, 34] Based on this information, we examined whether CD96 is involved in FAO regulation in BCSCs.