In the AALL0232 cohort, older age was associated with both hyperbilirubinemia (odds ratio [OR], 4.91 [95% CI, 3.37-7.14]; P < 1 × 10−16) and elevated ALT and AST levels (OR, 1.41 [95% CI, 1.18-1.68]; P = .0002) (Table 1). This evidence concerns the gene GPT and Hyperbilirubinemia.