The top motif enriched in upregulated peaks involved many transcription factors associated with tumor metastasis, such as AP-1 family members Fra1, JunB, Atf3, and Fos (Belguise et al., 2005; Hyakusoku et al., 2016; Milde-Langosch et al., 2004; Yuan et al., 2013). Here, ATF3 is linked to neoplasm.