Our consistent finding that insomnia in general is not associated with increased circulating cTn, in addition to our novel finding that the COMISA and insomnia with short sleep duration phenotypes are associated with increased cTnT, underscores the importance of comprehensively assessing multiple aspects of sleep in studies of insomnia and CVD to distinguish associations that may be driven by co-occurring sleep disturbances or disease sub-phenotypes. Here, TNNT2 is linked to sleep disorder.